Greek
atomism was purely philosophical in nature, with little concern for empirical
observations and no concern for chemical experiments.
In the Hellenistic world the art of alchemy first
proliferated, mingling magic and occultism into the study of natural substances
with the ultimate goal of transmuting elements into gold and discovering the
elixir of eternal life. Work, particularly the development of distillation,
continued in the early Byzantine period with the most famous practitioner being
the 4th century Greek-Egyptian Zosimos of Panopolis. Alchemy continued to be
developed and practised throughout the Arab world after the Muslim conquests, and
from there, and from the Byzantine remnants, diffused into medieval and
Renaissance Europe through Latin translations. Some influential Muslim chemists,
Abū al-Rayhān al-Bīrūnī, Avicenna and Al-Kindi refuted the theories of alchemy,
particularly the theory of the transmutation of metals; and al-Tusi described a
version of the conservation of mass, noting that a body of matter is able to
change but is not able to disappear.
Jābir ibn Hayyān (Geber), a Persian alchemist whose
experimental research laid the foundations of chemistry.
The development of the modern scientific method was slow and
arduous, but an early scientific method for chemistry began emerging among
early Muslim chemists, beginning with the 9th century Persian or Arabian
chemist Jābir ibn Hayyān (known as "Geber" in Europe), who is
sometimes referred to as "the father of chemistry". He introduced a
systematic and experimental approach to scientific research based in the
laboratory, in contrast to the ancient Greek and Egyptian alchemists whose
works were largely allegorical and often unintelligible. Under the influence of
the new empirical methods propounded by Sir Francis Bacon and others, a group
of chemists at Oxford, Robert Boyle, Robert Hooke and John Mayow began to
reshape the old alchemical traditions into a scientific discipline. Boyle in
particular is regarded as the founding father of chemistry due to his most
important work, the classic chemistry text The Sceptical Chymist where the
differentiation is made between the claims of alchemy and the empirical
scientific discoveries of the new chemistry. He formulated Boyle's law,
rejected the classical "four elements" and proposed a mechanistic
alternative of atoms and chemical reactions that could be subject to rigorous
experiment.

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